Princeton University Biological Safety Manual
Table of Contents
Preface
I. Introduction
A. Scope B. Regulatory Forces and Guidelines C. The Biological Safety Program at Princeton University The Institutional Biosafety Committee (IBC) ORPA Department Chairperson Principal Investigator Researcher or User EHS (Biosafety Officer) Employee Health Campus Veterinarian Other Committees
A. Scope B. Regulatory Forces and Guidelines C. The Biological Safety Program at Princeton University
The Institutional Biosafety Committee (IBC) ORPA Department Chairperson Principal Investigator Researcher or User EHS (Biosafety Officer) Employee Health Campus Veterinarian Other Committees
II. Research Project Registration and Approval
A. Introduction B. Registration and Approval Process C. Additional Approvals and Requirements Select Biological Agents and Toxins Live Viruses Human Blood and Tissue Biohazards Associated with Animal Handling
A. Introduction B. Registration and Approval Process C. Additional Approvals and Requirements
Select Biological Agents and Toxins Live Viruses Human Blood and Tissue Biohazards Associated with Animal Handling
A. Exposure Control B. Biosafety Levels C. Animal Biosafety Levels
A. Guidelines for Good Laboratory Practices at BSL1 and BSL2 B. Biological Safety Cabinets (BSC's) Types of BSC's Working in a BSC Certification of the BSC C. Decontamination Definitions When to Decontaminate Autoclave Use Chemical Disinfectant Use D. Exposure to Infectious Agents Intact Skin Broken, Cut or Damaged Skin or Puncture Wound Eye Ingestion or Inhalation E. Biological Material Spills Spills and Preparing for Them Spills Inside a Biological Safety Cabinet Small Spill of Material Outside a Biological Safety Cabinet Large Spill of BL2 Material (>500ml) Outside of a Biological Safety Cabinet F. Biological Waste Handling Biohazardous Waste (Regulated Medical Waste) Animal Bedding Waste Animal Carcasses Animal Waste from BSL2 Animal Room LTL 41 Patient Care Waste Disposal G. Packaging and Shipping Biological Materials Definitions Packaging Labeling H. Shipping and Transportation Methods and Requirements Registered Mail or the Equivalent Federal Express or UPS Damaged Packages Notice of Delivery Importation/Exportation of Etiologic Agents Other Permits
Types of BSC's Working in a BSC Certification of the BSC
C. Decontamination
Definitions When to Decontaminate Autoclave Use Chemical Disinfectant Use
D. Exposure to Infectious Agents
Intact Skin Broken, Cut or Damaged Skin or Puncture Wound Eye Ingestion or Inhalation
E. Biological Material Spills
Spills and Preparing for Them Spills Inside a Biological Safety Cabinet Small Spill of Material Outside a Biological Safety Cabinet Large Spill of BL2 Material (>500ml) Outside of a Biological Safety Cabinet
F. Biological Waste Handling
Biohazardous Waste (Regulated Medical Waste) Animal Bedding Waste Animal Carcasses Animal Waste from BSL2 Animal Room LTL 41 Patient Care Waste Disposal
G. Packaging and Shipping Biological Materials
Definitions Packaging Labeling
H. Shipping and Transportation Methods and Requirements
Registered Mail or the Equivalent Federal Express or UPS Damaged Packages Notice of Delivery Importation/Exportation of Etiologic Agents Other Permits
