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Radiation
Safety Manual for Laboratory Users
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APPENDIX
B: The Characteristics of Common Radioisotopes
This section provides useful information, including physical characteristics,
shielding needs, handling precautions and waste disposal information
for the six radioisotopes most commonly used at Princeton University:
For information about other radioisotopes, contact Environmental Health & Safety
(EHS).
| Isotope |
Half-life |
Emission |
Max. Energy (keV) |
ALI* for Ingestion (mCi) |
Badging Needed? |
Shielding |
Detection*** |
More Info |
| H-3 |
12.3y |
B- |
19 |
80 |
no |
none |
LSC only |
* |
| C-14 |
5730y |
B- |
156 |
2 |
no |
none** |
LSC;G-M |
* |
| P-32 |
14.3d |
B- |
1710 |
0.6 |
>5mCi |
Plexiglas |
G-M |
* |
| Si-32 |
104y |
|
|
|
|
|
|
* |
| P-33 |
25d |
B- |
250 |
6 |
no |
none** |
LSC |
* |
| S-35 |
87.4d |
B- |
167 |
10 |
no |
none** |
LSC |
* |
| Fe-55 |
2.7y |
|
|
|
|
|
|
* |
| Co-57 |
271.8d |
|
|
|
|
|
|
* |
| Fe-59 |
44.6d |
|
|
|
|
|
|
* |
| Ni-63 |
100.1y |
|
|
|
|
|
|
* |
| Zn-65 |
243.9d |
|
|
|
|
|
|
* |
| Se-75 |
119.8d |
|
|
|
|
|
|
* |
| Cd-109 |
462.6d |
|
|
|
|
|
|
* |
| I-125 |
60.1d |
X,g |
27-35 |
0.04 |
>1mCi |
lead |
NaI;g |
* |
| Hg-203 |
47d |
|
|
|
|
|
|
* |
Physical Characteristics:
- Half-life: 12.3 years
- Emissions: Beta particles with a
maximum energy of 18.6 keV and an average energy of 5.7 keV.
- Maximum Range in Air: 4.7 mm in air;
6 mm in tissue.
- Fraction transmitted through the dead layer
of the skin: none
Dose and Shielding:
- Dose rate to the skin at 10 cm: None
- Dose rate to epidermal basal cells from skin
contamination of 1 mCi/cm2: None
- Shielding: None needed.
- Annual Limit on Intake (ALI): 80 millicuries
via ingestion, assuming intake as tritiated
water. The ingestion of one ALI will produce a dose of 5
rem.
Detection:
Liquid scintillation counting is the preferred method for detecting
H-3. Most G-M detectors will not detect
the presence of H-3.
Precautions:
H-3 contamination cannot be detected with a G-M meter, and
special precautions are needed to keep the work environment
clean. The regular use of wipe testing,
using a liquid scintillation counter, is the only way
to insure that your work space does not contain contamination.
Waste Disposal:
- Solid Wastes/Liquid Scintillation Wastes: through the
Off-Site Radioactive Waste Disposal Program
- Liquid Wastes: through the Sewer Disposal
Program. The monthly secondary disposal limit is 3 mCi.
Carbon-14
Physical Characteristics
- Half-life: 5,730 years
- Emissions: Beta particles with a maximum
energy of 156 keV and an average energy of 49 keV.
- Maximum Range in Air: 22 cm in air;
0.027 cm in tissue.
- Fraction transmitted through the dead layer of
the skin: 0.11
Dose and Shielding:
- Dose rate to the skin at 10 cm: 600 mrad/hour/mCi
(for an unshielded point source)
- Dose rate to epidermal basal cells
from skin contamination of 1 mCi/cm2: 1400 mrad/hour
- Shielding: None needed, when used
in millicurie quantities under normal laboratory conditions.
- Annual Limit on Intake (ALI): 2
millicuries via ingestion. The ingestion of one ALI
will produce a dose of
5 rem.
Detection:
Liquid scintillation counting is the preferred method for detecting
C-14. Most G-M detectors are not likely
to detect the presence of C-14 in amounts less than about 100,000
dpm (0.05 µCi).
Precautions:
Low-level C-14 contamination cannot be easily detected with a
G-M meter, and special precautions are needed to keep the work
environment clean. The regular
use of wipe testing, using a liquid scintillation counter,
is the only way to insure that your work space does not contain
low-level removable contamination.
Waste Disposal:
- Solid Wastes/Liquid Scintillation Wastes: through the Off-Site
Radioactive Waste Disposal Program
- Liquid Wastes: through the Sewer Disposal
Program. The monthly secondary disposal limit is 3 mCi.
Phosphorus-32
Physical Characteristics:
- Half-life: 14.3 days
- Emissions: Beta particles with a maximum
energy of 1.71 MeV and an average energy of 0.7 MeV.
- Maximum Range: 620 cm in air; 0.8
cm in tissue; 0.6 cm in plexiglas
- Fraction transmitted through the dead layer
of the skin: 0.95
Dose and Shielding:
- Dose rate to the skin at 10 cm: 4070 mrad/hour/mCi
(for an unshielded point source)
- Dose rate to epidermal basal cells from
skin contamination of 1 mCi/cm2:
9200 mrad/hour
- Shielding: 3/8” plexiglas/lucite
will shield all P-32 betas. For high activity sources exceeding
a
few millicuries, it may be desirable to add lead shielding outside
the plexiglas shielding to shield against bremsstrahlung x-rays.
Plexiglas
should be placed closest to the P-32 source as primary shielding,
and lead should be used outside the plexiglas as secondary shielding.
- Annual Limit on Intake (ALI): 600
microcuries via ingestion. The intake of one ALI will produce a
dose of 5 rem.
Detection:
A G-M detector will readily detect low-level P-32 contamination,
although liquid scintillation counting is also an acceptable
method for detecting removable P-32
contamination.
Precautions:
High localized doses are possible while handling millicurie
amounts of P-32 and as a result of skin contamination.
Reduce doses by
wearing safety glasses (for
shielding the eyes), using remote handling tools such
as tongs, using shielding extensively to shield storage and
experimental
containers and work areas, and
performing thorough and frequent surveys of the work
area, clothing and the body.
Waste Disposal:
- Solid Wastes: through the Decay-in-Storage Program.
- Liquid Wastes: through the Sewer Disposal
Program. The monthly secondary disposal limit is 300 µCi.
Silicon-32
Physical Characteristics
- Half-life: 104 years
- Emissions: Beta particles with a maximum energy of
0.224 MeV and an average energy of 0.067 MeV. Since Si-32
decays to P-32, emissions
from a Si-32 source also
include the 1.71 MeV beta from P-32
- Maximum Range: 37 cm in air; <.05 cm in tissue.
- See the P-32 fact sheet for information about the properties
of the beta from the P-32 progeny.
Dose and Shielding
Dose rate to the skin at 10 cm: See the P-32
fact sheet for information
about the dose from the P-32 progeny.
Dose rate to epidermal basal
cells from skin contamination of 1 µCi/cm2: See the P-32
fact sheet for information
about the dose from the P-32
progeny.
Shielding: Depending on the age of the material, plexiglas shielding
may be required for the P-32 progeny.
Annual Limit on Intake (ALI): 2000 microcuries via ingestion
and 200 microcuries via inhalation. The intake of one ALI will
produce
a dose
of 5 rem.
Detection
Liquid scintillation counting is the preferred method for detecting
Si-32. Most G-M detectors are not likely to detect the presence
of Si-32 in
amounts less
than about 100,000 dpm (0.05 µCi). However, if the sample
is older than a week, it may be appropriate to use a G-M detector
to detect
the P-32
progeny.
Precautions
Appropriate precautions will depend on the age of the sample
of Si-32. A sample of Si-32 will reach equilibrium
with the P-32 progeny
in approximately 120
days, i.e., a 1 mCi sample of Si-32 will also contain
1 mCi P-32 in 120 days. Within
the first week, it is appropriate to take precautions
based on the properties of Si-32. However, after that point,
the sample
will contain
enough P-32,
that precautions based on the properties of P-32 should
be taken.
Low-level Si-32 contamination cannot be easily detected
with a G-M meter, and special precautions are needed
to keep the
work environment
clean.
The regular
use of wipe testing, using a liquid scintillation
counter, is the
only way to insure that the work space does not contain
low-level removable
contamination.
High localized doses are possible while handling
millicurie amounts of P-32 and as a result of skin
contamination.
Reduce doses by
wearing safety
glasses
(for
shielding the eyes), using remote handling tools
such as tongs, using shielding extensively to shield
storage
and
experimental
containers
and work areas, and
performing thorough and frequent surveys of the
work area, clothing and the body.
Radiation Monitoring Requirements: Radiation monitoring badges may be required for
Si-32 users, depending on the amount of Si-32
used.
Waste Disposal
Solid Wastes: through the Off-Site Radioactive Waste
Disposal Program.
Liquid Wastes: through the Sewer Disposal Program.
The monthly secondary disposal limit is 300 µCi.
Phosphorus-33
Physical Characteristics:
- Half-life: 25.3 days
- Emissions: Beta particles with a
maximum energy of 249 keV and an average energy of 76 keV.
- Maximum Range: 45 cm in air; 0.06
cm in tissue
- Fraction transmitted through the dead layer
of the skin: 0.35
Dose and Shielding:
- Dose rate to the skin at 10 cm: 2000 mrad/hour/mCi
(for an unshielded point source)
- Dose rate to epidermal basal cells from skin
contamination of 1 mCi/cm2: 4500 mrad/hour
- Shielding: None needed, when used
in millicurie quantities or less, under normal laboratory conditions
- Annual Limit on Intake (ALI): 6
millicuries via ingestion. The intake of one ALI
will produce a dose of 5 rem.
Detection:
Liquid scintillation counting is the preferred method for detecting
P-33. Most G-M detectors are not likely
to detect the presence of P-33 in amounts less than
about 100,000 dpm (0.05 µCi).
Precautions:
Low-level P-33 contamination cannot be easily detected
with a G-M meter, and special precautions are needed
to keep the
work
environment
clean. The regular
use of wipe testing, using a liquid scintillation
counter, is the only way to insure that the work space does
not contain low-level
removable contamination.
Waste Disposal:
- Solid Wastes: through the Decay-in-Storage Program.
- Liquid Wastes: through the Sewer Disposal
Program. The monthly secondary disposal limit is 3 mCi.
Sulfur-35
Physical Characteristics:
- Half-life: 87.6 days
- Emissions: Beta particles with a
maximum energy of 167 keV and an average energy of 49 keV.
- Maximum Range: 24 cm in air; 0.030
cm in tissue.
- Fraction transmitted through the dead layer
of the skin: 0.12
Dose and Shielding:
- Dose rate to the skin at 10 cm: 625 mrad/hour/mCi
(for an unshielded point source)
- Dose rate to basal cells from
skin contamination of 1 mCi/cm2: 1460 mrad/hr
- Shielding: None needed, when used
in millicurie quantities under normal laboratory conditions
- Annual Limit on Intake (ALI): 10
millicuries via ingestion for most compounds of sulfur. The intake
of one ALI
will produce a dose of 5 rem.
Detection:
Liquid scintillation counting is the preferred method
for detecting S-35. Most G-M detectors are not likely
to detect the presence
of S-35 in amounts less than
about 100,000 dpm (0.05 µCi).
Precautions:
- 35S-labeled methionine/cysteine compounds can volatilize.
Stock solutions and thawed materials should
be opened within a fume
hood. Activated
charcoal can
be used to trap contamination within equipment
such as incubators. Contact EHS for further information.
- Low-level
S-35 contamination cannot be easily detected with a G-M meter,
and special
precautions are needed
to keep the
work
environment
clean.
The regular
use of wipe testing, using a liquid scintillation
counter, is the only way to insure that
the work space does
not contain low-level
removable
contamination.
Waste Disposal:
- Solid Wastes: through the Decay-in Storage
Program
- Liquid Wastes: through the Sewer Disposal
Program. The monthly secondary disposal limit is 3 mCi.
Iron-55
Physical Characteristics
Half-life: 2.70 years
Emissions: Principal emissions are a 6 keV x-ray and 5.2 keV [average]
Auger electrons.
Electron Maximum Range: 0.15 cm in air; 0.0 cm in tissue
Dose and Shielding
Dose rate at 10 cm: negligible
Dose rate to basal cells from skin contamination
of 1 µCi/cm2: 59
mrem/hr
Shielding: None needed, when used in millicurie quantities, under
normal laboratory operations.
Annual Limit on Intake (ALI): 2,000 microcuries via inhalation,
and 9,000 microcuries via ingestion. The intake of one ALI will
produce a dose
of 5 rem.
Detection
Liquid scintillation counting is the preferred method for detecting
Fe-55 contamination, although a low energy sodium iodide crystal
scintillation
detector will also
detect Fe-55 with a lower efficiency. The regular use of wipe testing,
using a liquid scintillation counter, is the only way to insure that
the work space
does not contain low-level removable contamination.
Precautions
External radiation from Fe-55 is low energy and does not normally
present an external exposure hazard. Low-level Fe-55 contamination
is not readily
detected
with a survey meter, and special precautions are needed to keep the
work environment clean. The regular use of wipe testing, using
a liquid scintillation
counter,
is the only way to insure that your work space does not contain low-level
removable contamination.
Radiation Monitoring Requirements: Radiation monitoring badges are not required for Fe-55 users.
Waste Disposal
Solid Wastes: through the Off-Site Radioactive Waste Disposal Program.
Liquid Wastes: through the Sewer Disposal Program. The monthly secondary
disposal limit is 3 mCi.
Cobalt-57
Physical Characteristics
Half-life: 271.8 days
Emissions: Principal emissions are 122 keV gammas (86%) and 137 keV
gammas (11%), accompanied by electrons with energies ranging up to
7 keV
Half-Value Layer: < 1 mm lead
The half-value layer is the amount of material required to reduce the radiation
intensity by 50%.
Dose and Shielding
Gamma dose rate (deep tissue dose) at 30 cm: 0.93mrem/hour per millicurie
at 30 cm (for an unshielded point source)
Dose rate to epidermal basal cells from skin
contamination of 1 µCi/cm2: 444 mrem/hr
Shielding: Lead foil or sheets, when used in hundreds of microcuries
or in millicurie quantities.
Annual Limit on Intake (ALI): 4000 microcuries via ingestion and 700
microcuries via inhalation. The ingestion of one ALI will produce a
dose of 5 rem.
Detection
A sodium iodide crystal scintillation detector is the preferred method
for detecting Co-57. Additionally a G-M detector will detect Co-57
contamination with a significantly
lower efficiency of detection. Liquid scintillation counting is
also an acceptable
method for detecting removable contamination.
Precautions
High localized doses are possible while handling Co-57 and as a
result of skin contamination. Reduce doses by using remote handling
tools
such as tongs,
using
shielding extensively to shield storage and experimental containers
and work areas, and performing thorough and frequent surveys
of the work
area, clothing
and the body.
Radiation Monitoring Requirements: Radiation monitoring badges must
be worn by any person who uses open sources of Co-57 in amounts of
0.5 mCi or more for extended
operations
(applies to
most operations other than simple aliquoting from a stock vial).
Waste Disposal
Solid Wastes/Liquid Scintillation Wastes: through the Off-Site
Radioactive Waste Disposal Program
Liquid Wastes: through the Sewer Disposal Program. The monthly
secondary disposal limit is 3 mCi.
Iron-59
Physical Characteristics
Half-life: 44.6 days
Emissions:
Beta particles: 0.273 MeV (46%) and 0.466 MeV (53%) maximum
energies with average energies of 0.081 MeV and 0.149 MeV respectively.
Gamma rays: 1.099 MeV (56%) and 1.292 MeV (44%).
Beta Maximum Range: ~ 100 cm in air; 0.14 cm in tissue; 0.12 cm in plexiglas
Fraction transmitted through the dead layer
of the skin: 0.95
Half-Value Layer: 15 mm lead
The half-value layer is the amount of material required to reduce
the radiation intensity by 50%.
Dose and Shielding
Gamma dose rate (deep tissue dose) at 30 cm: 7.0 mrem/hour/mCi (for
an unshielded point source)
Beta dose rate to the skin at 30 cm: 130 mrem/hour/mCi (for an
unshielded point source)
Dose rate to epidermal basal cells from skin
contamination of 1 µCi/cm2: 3593 mrem/hour
Shielding: Generally, lead is the preferred shielding material for
Fe-59 for lower activity operations. However, it may be desirable to
use a
combination of plexiglas and lead/steel as shielding when working with
multi-millicurie
amounts
to minimize the amount of bremsstrahlung produced by the betas. In
such a case, plexiglas should be placed closest to the source as primary
shielding,
and lead
should be used outside the plexiglas as secondary shielding.
Annual Limit on Intake (ALI): 800 microcuries via ingestion and 300
via inhalation. The intake of one ALI will produce a dose of 5 rem.
Detection
A sodium iodide crystal scintillation detector is the preferred method
for detecting Fe-59. Additionally a G-M detector will readily detect
Fe-59 contamination, although
liquid scintillation counting is also an acceptable method for
detecting removable contamination.
Precautions
High localized doses are possible while handling Fe-59 and as a
result of skin contamination. Reduce doses by wearing safety
glasses (for
shielding the eyes),
using remote handling tools such as tongs, using shielding
extensively to shield storage and experimental containers and work
areas,
and performing thorough and
frequent surveys of the work area, clothing and the body.
Radiation Monitoring Requirements: Radiation
monitoring badges must be worn by any person who uses
open sources of Fe-59 in amounts of 0.5 mCi or more
for extended
operations
(applies
to most operations other than simple aliquoting from
a stock vial).
Waste Disposal
Solid Wastes: through the Decay-in-Storage Program
Liquid Wastes: through the Sewer Disposal Program. The monthly
secondary disposal limit is 300 µCi.
Nickel-63
Physical Characteristics
Half-life: 100.1 years
Emissions: Beta particles with a maximum energy of 66 keV and an average
energy of 17 keV
Maximum Range in Air: 5 cm in air; < 0.01 cm in tissue.
Dose and Shielding
Dose rate to the skin at 10 cm: negligible (for an unshielded point
source)
Dose rate to epidermal basal cells from skin
contamination of 1 µCi/cm2: negligible
Shielding: None needed.
Annual Limit on Intake (ALI): 9000 microcuries via ingestion and 2000
microcuries via inhalation. The ingestion of one ALI will produce a dose
of 5 rem.
Detection
Liquid scintillation counting is the preferred method for detecting
Ni-63. G-M detectors will not detect Ni-63 contamination.
Precautions
Ni-63 contamination cannot be detected with a G-M meter, and special
precautions are needed to keep the work environment clean. The
regular use of wipe
testing, using a liquid scintillation counter, is the only way
to insure that your
work space does not contain low-level removable contamination.
Radiation Monitoring Requirements: Radiation monitoring badges are not required for Ni-63 users, since
the monitoring badges will not detect Ni-63.
Waste Disposal
Solid Wastes/Liquid Scintillation Wastes: through the Off-Site
Radioactive Waste Disposal Program
Liquid Wastes: through the Sewer Disposal Program. The monthly
secondary disposal limit is 3 mCi.
Zinc-65
Physical Characteristics
Half-life: 243.9 days
Emissions: Beta (positron) particles
with a maximum energy of 0.33 MeV (2%) and an average energy
of 0.099 MeV. Gamma rays: 1.116 MeV
(51%) and 0.511 MeV (2%).
Beta Maximum Range: 76.2 cm in
air; 0.10 cm in tissue; 0.08 cm in plexiglas
Fraction transmitted through the dead layer
of the skin: 0.95
Half-Value Layer: 14 mm lead; 2 cm
in tissue
The half-value layer is the amount of material required to
reduce the radiation intensity by 50%.
Dose and Shielding
Beta Dose rate to the skin at 30 cm: 1.93 mrem/hour/mCi (for an unshielded
point source)
Gamma Dose rate (deep tissue dose) at 30 cm: 3.44 mrem/hour/mCi (for
an unshielded point source)
Dose rate to epidermal basal cells from skin
contamination of 1 µCi/cm2: 281 mrem/hour
Shielding: Shield stock vials with lead. Generally, lead is the preferred
shielding material for Zn-65 for lower activity operations. However,
since significant
bremsstrahlung may be produced with higher activities, it may be desirable
to use a combination of plexiglas and lead/steel as shielding when working
with
multi-millicurie amounts. In such a case, plexiglas should be placed
closest to the source as primary shielding, and lead should be used outside
the
plexiglas as secondary shielding.
Annual Limit on Intake (ALI): 400 microcuries via ingestion and 300 microcuries
via inhalation. The intake of one ALI will produce a dose of 5 rem.
Detection
A G-M detector will readily detect low-level Zn-65 contamination, although
liquid scintillation counting is also an acceptable method for detecting
removable contamination.
Precautions
High localized doses are possible while handling millicurie amounts
of Zn-65 and as a result of skin contamination. Reduce doses
by wearing safety glasses
(for shielding the eyes), using remote handling tools such
as tongs, using shielding extensively to shield storage and experimental
containers
and
work areas, and
performing thorough and frequent surveys of the work area,
clothing and
the body.
Radiation Monitoring Requirements: Radiation monitoring badges must be worn by any person who uses open
sources of Zn-65 in amounts of 0.5 mCi or more for extended operations
(applies
to most operations other than simple aliquoting from a stock vial).
Waste Disposal
Solid Wastes: through the Off-Site Radioactive Waste Disposal Program
Liquid Wastes: through the Sewer Disposal Program. The monthly
secondary disposal limit is 300 µCi.
Selenium-75
Physical Characteristics
Half-life: 119.8 days
Emissions: Principal emissions are 136 keV and 265 keV x-rays.
Half-Value Layer: 0.02 mm lead; 2 cm in tissue
The half-value layer is the amount of material required to reduce the
radiation intensity by 50%.
Dose and Shielding
Gamma Dose rate (deep tissue dose) at 30 cm: 2.74 mrem/hour/mCi (for
an unshielded point source)
Dose rate to epidermal basal cells from skin
contamination of 1 µCi/cm2: 519 mrem/hour
Shielding: Lead foil or sheets, when used in hundreds of microcuries or
in millicurie quantities. None needed when used in low microcurie amounts.
Annual Limit on Intake (ALI): 700 microcuries via inhalation, and 500 microcuries
via ingestion. The intake of one ALI will produce a dose of 5 rem.
Detection
A sodium iodide crystal scintillation detector is the preferred method
for detecting Se 75. Additionally a G-M detector will readily detect
Se-75 contamination,
although
liquid scintillation counting is also an acceptable method for detecting
removable contamination.
Precautions
High localized doses are possible while handling millicurie amounts
of Se-75 and as a result of skin contamination. Reduce doses by using
remote
handling
tools such as tongs, using shielding extensively to shield storage
and experimental containers and work areas, and performing thorough
and frequent
surveys of
the work area, clothing and the body.
Radiation Monitoring Requirements: Radiation monitoring badges must be worn by any person who uses open
sources of Se-75 in amounts of 0.5 mCi or more for extended operations
(applies
to most operations other than simple aliquoting from a stock vial).
Waste Disposal
Solid Wastes: through the Decay-in-Storage Program.
Liquid Wastes: through the Sewer Disposal Program. The monthly
secondary disposal limit is 3 mCi.
Cadmium-109
Physical Characteristics
Half-life: 462.6 days
Emissions: Principal emissions are 22.1 keV x-rays (83%), accompanied
by electrons with energies ranging up to 87 keV.
Half-Value Layer: 0.01 mm lead; 2 cm in tissue
The half-value layer is the amount of material required to reduce the radiation
intensity by 50%.
Dose and Shielding
Beta dose rate to the skin at 30 cm: 0 mrem/hour/mCi (for an unshielded
point source)
Gamma Dose rate (deep tissue dose) at 30 cm: 0.778 mrem/hour/mCi (for
an unshielded point source)
Dose rate to epidermal basal cells from skin
contamination of 1 µCi/cm2: 2000 mrem/hour
Shielding: Lead foil or sheets are used to shield the x-rays (the electrons
are too low in energy to require shielding) when Cd-109 is used in
hundreds of microcuries
or in millicurie quantities. Shielding is not needed when Cd-109 is
used in low microcurie amounts.
Annual Limit on Intake (ALI): 40 microcuries via inhalation, and 300
microcuries via ingestion. The intake of one ALI will produce a dose
of 5 rem. The
critical organ for protection are the kidneys.
Detection
A sodium iodide crystal scintillation detector is the preferred method
for detecting Cd-109. G-M detectors are not likely to detect the
presence of Cd-109 in amounts
less than about 100,000 dpm (0.05 µCi).
Precautions
Skin contamination and ingestion are the chief concerns when working
with Cd-109, and appropriate precautions must be taken to limit
contamination. Contamination
of work areas and individuals is a more significant hazard
than the external dose, unless working with millicurie quantities.
Radiation Monitoring Requirements: Radiation monitoring badges must be worn by any person who
uses open sources of Cd-109 in amounts of 1 mCi or more for
extended
operations
(applies
to most operations other than simple aliquoting from a stock
vial).
Waste Disposal
Solid Wastes: through the Off-Site Radioactive Waste Disposal
Program.
Liquid Wastes: through the Sewer Disposal Program. The
monthly secondary disposal limit is 300 µCi.
Iodine-125
Physical Characteristics:
- Half-life: 60.1 days
- Emissions: Principal emissions are
a 35 keV gamma ray and 27 - 32 keV x-rays.
- Half-Value Layer: 0.02 mm lead; 2
cm in tissue. (The half-value layer is the amount of material required
to reduce the radiation intensity by 50%.)
Dose and Shielding:
- Dose rate at 10 cm: 15 mrem/hour/mCi
(for an unshielded point source)
- Shielding: Lead foil or sheets, when
used in hundreds of microcuries or in millicurie quantities.
None needed
when used in low microcurie
amounts such
as for RIA kits.
- Annual Limit on Intake (ALI): 60 microcuries
via inhalation, and 40 microcuries via ingestion. The intake
of one ALI
will produce
a dose of 5 rem. The critical
organ for protection is the thyroid gland.
Detection:
A sodium iodide crystal scintillation detector is the
preferred method for detecting I-125. G-M detectors
are not likely
to detect the presence of I-125
in amounts less than about 100,000 dpm (0.05 µCi).
Precautions:
Volatile iodine can be released from Na125I or from
iodinated compounds containing hundreds of microcuries
or more
of I-125. Containers
of I-125, including sample
vials of iodinated compounds, should always be opened
in a fume hood. Personnel using I-125 in hundreds of
microcuries
or more
must wear double gloves and
should change gloves as soon as the gloves become contaminated. Iodinations must be performed under EHS surveillance
and thyroid
count bioassays must be
performed following an iodination.
Waste Disposal:
- Solid Wastes: through the Decay-in-Storage Program.
- Liquid Wastes: through the Sewer Disposal
Program. The monthly secondary disposal limit is 30 µCi.
Mercury-203
Physical Characteristics
Half-life: 47 days
Emissions: Beta particles: 0.210 MeV maximum energy (100 %) and
0.070 MeV average energy.
Gamma rays: 0.279 MeV (100%).
Beta Maximum Range: 34 cm in air; 0.04 cm in tissue; 0.04 cm
in plexiglas
Dose and Shielding
Dose rate to the skin at 30 cm: 15.2 mrem/hour/mCi (for an unshielded
point source)
Gamma Dose rate (deep tissue dose) at 30 cm: 1.63 mrem/hour/mCi (for
an unshielded point source)
Dose rate to epidermal basal cells from skin
contamination of 1 µCi/cm2: 3296 mrem/hour
Shielding: Shield stock vials with lead.
Half-Value Layer: 0.2 cm lead
The half-value layer is the amount of material required to reduce the
radiation intensity by 50%.
Annual Limit on Intake (ALI): 500 microcuries via ingestion and 800
microcuries via inhalation. The intake of one ALI will produce a dose
of 5 rem.
Detection
A G-M detector will readily detect low-level Hg-203 contamination,
although liquid scintillation counting is also an acceptable method
for detecting
removable contamination.
Precautions
High localized doses are possible while handling millicurie amounts
of Hg-203 and as a result of skin contamination. Reduce doses
by wearing safety glasses
(for shielding the eyes), using remote handling tools such
as tongs, using shielding extensively to shield storage and experimental
containers and
work areas, and
performing thorough and frequent surveys of the work area,
clothing
and
the body.
Radiation Monitoring Requirements: Radiation monitoring badges must be worn by any person who
uses open sources of Hg-203 in amounts of 0.5 mCi or more
for extended
operations
(applies
to most operations other than simple aliquoting from a stock
vial).
Waste Disposal
Solid Wastes: through the Decay-in-Storage Program
Liquid Wastes: through the Sewer Disposal Program. The monthly
secondary disposal limit is 3 mCi.
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